Аннотация:
2-Propyl-N′-[1,7,7-trimethylbicyclo[2.2.1]hept-2-ylidene]pentanehydrazide was obtained
in 80% yield via the Einhorn variation of the Schotten–Baumann method by (+)-camphor hydrazide
condensation with valproic acid (VPA) chloride. The structure of the titled compound was verified
by Raman, FTIR,
1H-NMR, and13C-NMR spectral analysis along with FAB-mass spectrometry.
Thermal properties of synthesized derivative were elucidated by DSC and its purity by HPLC.
The compound was successfully tested as a potential anticonvulsant agent based on models of
chemically- and electrically-induced seizures.
